_id

690db61bccc777a4e85d0e07

Ticker

BCYC

Name

Bicycle Therapeutics Ltd

Exchange

NASDAQ

Address

Portway Building, Cambridge, United Kingdom, CB21 6GS

Country

USA

Sector

Healthcare

Industry

Biotechnology

Currency

USD

Website

https://www.bicycletherapeutics.com

Description

Bicycle Therapeutics plc, a clinical-stage pharmaceutical company, develops a class of medicines for diseases that are underserved by existing therapeutics in the United States and the United Kingdom. The company's products pipeline include zelenectide pevedotin, a bicycle toxin conjugate (BTC), which is in phase I/II/III clinical trials for the treatment of high nectin-4 expressing tumors; BT5528 (EphA2), a BTC that is in phase I/II clinical trials to treat Ephrin type A receptor 2 expressing tumor; and BT7480, a Bicycle tumor-targeted immune cell agonist molecule, which is in phase I/II targeting nectin-4 and agonizing CD137. In addition, it develops Novel CNS targets, which is in preclinical trial targeting CNS disease; Novel neuromuscular targets, which is in preclinical trial targeting neuromuscular disease; and programs that is in preclinical trial targeting radiopharmaceutical. Further, the company collaborates with biopharmaceutical companies and organizations to develop programs in therapeutic areas. It has collaboration and license agreement with Bayer Consumer Care AG; Novartis Pharma AG; Ionis Pharmaceuticals, Inc.; and Genentech, Inc. Bicycle Therapeutics plc was incorporated in 2009 and is headquartered in Cambridge, the United Kingdom.

Last Close

7.45

Volume

315911

Current Price

7.33

Change

-1.6107382550335587

Last Updated

2025-11-28T12:46:56.981Z

Image

data:image/webp;base64,UklGRkQBAABXRUJQVlA4IDgBAADwCACdASpAAEAAPrVOo0wnJCMiKBgLUOAWiWkABmgXAloafYzOmt67BwxSd0kgcnskIoKbPMGZR4yWn7qDEYNg95rPVibSPVoGe9r1TprUAAD++KQs/q30VwyHEPxBtna//QD2Qt7vDopjq7r79GvBPzLsJCOe//y4iC1NBw0Z6r81t7MbwSNyZb2L3739A6izUau7NvJFH7VtAm7ufwH4Lq4DHSpfJ7cSHYxsKbSZQ9sGN354ezOax7aL5mMl2/nq9d9j7DFcCeuU/bGfhuP/IVPp4cmBBErp2JqChbYNpRG8LBgaOWoG2XSsoy/39DamcMfguarMs+DIb4l1kgUxVX4E8MjTEHLLSdYgYj1N54OTCfptgcbtqrV8MaTjUS9feqmF3BgMsCCRXwVwF78a3VY+CQkAAAA=

Ipo Date

2019-05-23T00:00:00.000Z

Market Cap

507079328

Next Dividend Date

-

Dividend Frequency

-

Dividend Rate

-

Dividend Yield

0

Sentiment

-0.148

Sentiment Sources

2

Rating

4.1539

Target Price

20.8182

Strong Buy

5

Buy

5

Hold

3

Sell

0

Strong Sell

0

Current Quarter

2025-09-30

Revenue

11734000

Cost Of Revenue

-

Gross Profit

11734000

Operating Expenses

77285000

Operating Income

-65551000

Interest Expense

44000

Pretax Income

-58895000

Net Income

-59100000

Eps

-0.8527677565942828

Dividends Per Share

-

Shares Outstanding

49929952

Income Tax Expense

205000

EBITDA

-57095000

Operating Margin

-558.6415544571331

Total Other Income Expense Net

6656000

Cash

648325000

Short Term Investments

-

Receivables

-

Inventories

-

Total Current Assets

738819000

Property Plant Equipment

11423000

Total Assets

763954000

Payables

12653000

Short Term Debt

-

Long Term Debt

-

Total Liabilities

145475000

Equity

618479000

Depreciation

1756000

Change In Working Capital

-22554000

Cash From Operations

-71173000

Capital Expenditures

674000

Cash From Investing

-674000

Cash From Financing

-30000

Net Change In Cash

-73126000

PE

-

PB

0.8348107335899845

ROE

-9.55570035522629

ROA

-7.73606787843247

FCF

-71847000

Fcf Percent

-6.122975967274587

Piotroski FScore

0

Health Score

33

Deep Value Investing Score

6.5

Defensive Investing Score

7

Dividend Investing Score

1.5

Economic Moat Investing Score

5.3

Garp Investing Score

4.5

Growth Investing Score

3

Momentum Investing Score

5.5

Net Net Investing Score

6

Quality Investing Score

3

Value Investing Score

7

Quarters > 0 > quarter

2025-09-30

Quarters > 0 > income Statement > revenue

11734000

Quarters > 0 > income Statement > cost Of Revenue

-

Quarters > 0 > income Statement > gross Profit

11734000

Quarters > 0 > income Statement > operating Expenses

77285000

Quarters > 0 > income Statement > operating Income

-65551000

Quarters > 0 > income Statement > interest Expense

44000

Quarters > 0 > income Statement > pretax Income

-58895000

Quarters > 0 > income Statement > net Income

-59100000

Quarters > 0 > income Statement > eps

-0.8527677565942828

Quarters > 0 > income Statement > dividends Per Share

-

Quarters > 0 > income Statement > shares Outstanding

69303746

Quarters > 0 > income Statement > income Tax Expense

205000

Quarters > 0 > income Statement > EBITDA

-57095000

Quarters > 0 > income Statement > operating Margin

-558.6415544571331

Quarters > 0 > income Statement > total Other Income Expense Net

6656000

Quarters > 0 > balance Sheet > cash

648325000

Quarters > 0 > balance Sheet > short Term Investments

-

Quarters > 0 > balance Sheet > receivables

-

Quarters > 0 > balance Sheet > inventories

-

Quarters > 0 > balance Sheet > total Current Assets

738819000

Quarters > 0 > balance Sheet > property Plant Equipment

11423000

Quarters > 0 > balance Sheet > total Assets

763954000

Quarters > 0 > balance Sheet > payables

12653000

Quarters > 0 > balance Sheet > short Term Debt

-

Quarters > 0 > balance Sheet > long Term Debt

-

Quarters > 0 > balance Sheet > total Liabilities

145475000

Quarters > 0 > balance Sheet > equity

618479000

Quarters > 0 > cash Flow > net Income

-59100000

Quarters > 0 > cash Flow > depreciation

1756000

Quarters > 0 > cash Flow > change In Working Capital

-22554000

Quarters > 0 > cash Flow > cash From Operations

-71173000

Quarters > 0 > cash Flow > capital Expenditures

674000

Quarters > 0 > cash Flow > cash From Investing

-674000

Quarters > 0 > cash Flow > cash From Financing

-30000

Quarters > 0 > cash Flow > net Change In Cash

-73126000

Quarters > 0 > ratios > PE

-0.8527677565942828

Quarters > 0 > ratios > PB

0.8348107335899845

Quarters > 0 > ratios > ROE

-9.55570035522629

Quarters > 0 > ratios > ROA

-7.73606787843247

Quarters > 0 > ratios > FCF

-71847000

Quarters > 0 > ratios > Piotroski FScore

0

Quarters > 0 > ratios > fcf Percent

-6.122975967274587

Quarters > 0 > health Score

33

Quarters > 1 > quarter

2025-06-30

Quarters > 1 > income Statement > revenue

2920000

Quarters > 1 > income Statement > cost Of Revenue

71029000

Quarters > 1 > income Statement > gross Profit

-68109000

Quarters > 1 > income Statement > operating Expenses

18493000

Quarters > 1 > income Statement > operating Income

-86602000

Quarters > 1 > income Statement > interest Expense

54000

Quarters > 1 > income Statement > pretax Income

-79183000

Quarters > 1 > income Statement > net Income

-78952000

Quarters > 1 > income Statement > eps

-1.1400680087129313

Quarters > 1 > income Statement > dividends Per Share

-

Quarters > 1 > income Statement > shares Outstanding

69252009

Quarters > 1 > income Statement > income Tax Expense

-231000

Quarters > 1 > income Statement > EBITDA

-77433000

Quarters > 1 > income Statement > operating Margin

-2965.821917808219

Quarters > 1 > income Statement > total Other Income Expense Net

7419000

Quarters > 1 > balance Sheet > cash

721451000

Quarters > 1 > balance Sheet > short Term Investments

-

Quarters > 1 > balance Sheet > receivables

60753000

Quarters > 1 > balance Sheet > inventories

-

Quarters > 1 > balance Sheet > total Current Assets

804262000

Quarters > 1 > balance Sheet > property Plant Equipment

14112999

Quarters > 1 > balance Sheet > total Assets

832184000

Quarters > 1 > balance Sheet > payables

18262999

Quarters > 1 > balance Sheet > short Term Debt

5432000

Quarters > 1 > balance Sheet > long Term Debt

-

Quarters > 1 > balance Sheet > total Liabilities

163269000

Quarters > 1 > balance Sheet > equity

668915000

Quarters > 1 > cash Flow > net Income

-78952000

Quarters > 1 > cash Flow > depreciation

1696000

Quarters > 1 > cash Flow > change In Working Capital

-4634000

Quarters > 1 > cash Flow > cash From Operations

-72786000

Quarters > 1 > cash Flow > capital Expenditures

498000

Quarters > 1 > cash Flow > cash From Investing

-498000

Quarters > 1 > cash Flow > cash From Financing

-45000

Quarters > 1 > cash Flow > net Change In Cash

-71522000

Quarters > 1 > ratios > PE

-1.1400680087129313

Quarters > 1 > ratios > PB

0.7712900249658029

Quarters > 1 > ratios > ROE

-11.802994401381342

Quarters > 1 > ratios > ROA

-9.487324918527634

Quarters > 1 > ratios > FCF

-73284000

Quarters > 1 > ratios > Piotroski FScore

1

Quarters > 1 > ratios > fcf Percent

-25.0972602739726

Quarters > 1 > health Score

34

Quarters > 2 > quarter

2025-03-31

Quarters > 2 > income Statement > revenue

9977000

Quarters > 2 > income Statement > cost Of Revenue

57271000

Quarters > 2 > income Statement > gross Profit

-47294000

Quarters > 2 > income Statement > operating Expenses

22910000

Quarters > 2 > income Statement > operating Income

-70204000

Quarters > 2 > income Statement > interest Expense

51000

Quarters > 2 > income Statement > pretax Income

-61841000

Quarters > 2 > income Statement > net Income

-60754000

Quarters > 2 > income Statement > eps

-0.877986737709302

Quarters > 2 > income Statement > dividends Per Share

-

Quarters > 2 > income Statement > shares Outstanding

69196945

Quarters > 2 > income Statement > income Tax Expense

-1087000

Quarters > 2 > income Statement > EBITDA

-70204000

Quarters > 2 > income Statement > operating Margin

-703.6584143530118

Quarters > 2 > income Statement > total Other Income Expense Net

8363000

Quarters > 2 > balance Sheet > cash

792972999

Quarters > 2 > balance Sheet > short Term Investments

-

Quarters > 2 > balance Sheet > receivables

46374000

Quarters > 2 > balance Sheet > inventories

-

Quarters > 2 > balance Sheet > total Current Assets

856086000

Quarters > 2 > balance Sheet > property Plant Equipment

15448000

Quarters > 2 > balance Sheet > total Assets

883894000

Quarters > 2 > balance Sheet > payables

11107000

Quarters > 2 > balance Sheet > short Term Debt

5716000

Quarters > 2 > balance Sheet > long Term Debt

-

Quarters > 2 > balance Sheet > total Liabilities

143561000

Quarters > 2 > balance Sheet > equity

740333000

Quarters > 2 > cash Flow > net Income

-60987262

Quarters > 2 > cash Flow > depreciation

1640273

Quarters > 2 > cash Flow > change In Working Capital

-35675450

Quarters > 2 > cash Flow > cash From Operations

-86701613

Quarters > 2 > cash Flow > capital Expenditures

606316

Quarters > 2 > cash Flow > cash From Investing

-606319

Quarters > 2 > cash Flow > cash From Financing

-41157

Quarters > 2 > cash Flow > net Change In Cash

-86547000

Quarters > 2 > ratios > PE

-0.877986737709302

Quarters > 2 > ratios > PB

0.6963315700502342

Quarters > 2 > ratios > ROE

-8.2063071617772

Quarters > 2 > ratios > ROA

-6.873448626192734

Quarters > 2 > ratios > FCF

-87307929

Quarters > 2 > ratios > Piotroski FScore

0

Quarters > 2 > ratios > fcf Percent

-8.750920016036885

Quarters > 2 > health Score

33

Quarters > 3 > quarter

2024-12-31

Quarters > 3 > income Statement > revenue

3708000

Quarters > 3 > income Statement > cost Of Revenue

56072000

Quarters > 3 > income Statement > gross Profit

-52364000

Quarters > 3 > income Statement > operating Expenses

15299000

Quarters > 3 > income Statement > operating Income

-67663000

Quarters > 3 > income Statement > interest Expense

52000

Quarters > 3 > income Statement > pretax Income

-52951168

Quarters > 3 > income Statement > net Income

-51854000

Quarters > 3 > income Statement > eps

-0.7509440927235076

Quarters > 3 > income Statement > dividends Per Share

-

Quarters > 3 > income Statement > shares Outstanding

69051745

Quarters > 3 > income Statement > income Tax Expense

-1082000

Quarters > 3 > income Statement > EBITDA

-65959000

Quarters > 3 > income Statement > operating Margin

-1824.7842502696874

Quarters > 3 > income Statement > total Other Income Expense Net

14711832

Quarters > 3 > balance Sheet > cash

879520000

Quarters > 3 > balance Sheet > short Term Investments

-

Quarters > 3 > balance Sheet > receivables

35653000

Quarters > 3 > balance Sheet > inventories

-

Quarters > 3 > balance Sheet > total Current Assets

928605000

Quarters > 3 > balance Sheet > property Plant Equipment

17189000

Quarters > 3 > balance Sheet > total Assets

956868000

Quarters > 3 > balance Sheet > payables

15793000

Quarters > 3 > balance Sheet > short Term Debt

5503000

Quarters > 3 > balance Sheet > long Term Debt

-

Quarters > 3 > balance Sheet > total Liabilities

163808000

Quarters > 3 > balance Sheet > equity

793060000

Quarters > 3 > cash Flow > net Income

-51854000

Quarters > 3 > cash Flow > depreciation

1688200

Quarters > 3 > cash Flow > change In Working Capital

35931000

Quarters > 3 > cash Flow > cash From Operations

-9396000

Quarters > 3 > cash Flow > capital Expenditures

368000

Quarters > 3 > cash Flow > cash From Investing

-368000

Quarters > 3 > cash Flow > cash From Financing

203000

Quarters > 3 > cash Flow > net Change In Cash

-11342000

Quarters > 3 > ratios > PE

-0.7509440927235076

Quarters > 3 > ratios > PB

0.6486716014551233

Quarters > 3 > ratios > ROE

-6.53847123798956

Quarters > 3 > ratios > ROA

-5.419138271945555

Quarters > 3 > ratios > FCF

-9764000

Quarters > 3 > ratios > Piotroski FScore

1

Quarters > 3 > ratios > fcf Percent

-2.633225458468177

Quarters > 3 > health Score

34

Valuation > metrics > PE

-0.8527677565942828

Valuation > metrics > PB

0.8348107335899845

Valuation > final Score

70

Valuation > verdict

16.5% Undervalued

Profitability > metrics > ROE

-9.55570035522629

Profitability > metrics > ROA

-7.999252861661652

Profitability > metrics > Net Margin

-5.036645645133799

Profitability > final Score

0

Profitability > verdict

Weak

Risk > metrics > Debt Equity

0.23521413014831546

Risk > metrics > Interest Coverage

-1489.7954545454545

Risk > final Score

-5899

Risk > verdict

High

Liquidity > metrics > Current Ratio

58.39081640717616

Liquidity > metrics > Quick Ratio

58.39081640717616

Liquidity > final Score

100

Liquidity > verdict

Great

Prev Valuations > 0

70

Prev Valuations > 1

70

Prev Valuations > 2

70

Prev Profitabilities > 0

0

Prev Profitabilities > 1

0

Prev Profitabilities > 2

0

Prev Risks > 0

-6355

Prev Risks > 1

-5446

Prev Risks > 2

-5145

Prev Liquidities > 0

100

Prev Liquidities > 1

100

Prev Liquidities > 2

100

Updated At

2025-12-16T12:14:12.656Z